Monitoring TB treatment - further update

More information from the Italian study;

All patients who showed a significant decline in IFN-y concentrations and became QFT-G negative after treatment had a complete clinical and microbiological recovery of the TB disease.

Among the 11 patients with persistent positive QFT-G results, 6 patients were considered as ‘responders to treatment’ on the basis of clinical, radiological, microbiological and laboratory findings; the remaining 5 patients, who had persistent culture positive samples after 2 months, did not have a complete resolution of the clinical disease and early relapsed after the 6-month treatment completion