...TST was positive in 388 subjects (37.2%), while QFT-G was positive in 7.6% (30/394).Importantly they found that the combination of QFT with a CT scan was more effective than the "conventional" method of TST and X-ray.
...Compared to the conventional approach, the additional use of QFT-G in TST-positive subjects and chest CT in subgroups with a high probability of infection was found to be more effective in the differentiation between active TB, latent TB and non-infected subjects in a contact investigation.
Given the relatively small numbers of QFT+ the additional use of a CT scan could provide a modern and cost effective solution to the issue of determining infection status.
Quantiferon is approved in Korea with a reimbursement of 67,000 Won (AU$68.75)
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