You could wonder what possible benefit is obtained from persisting with the antiquated TST; QFT in kiwi
haemodialysis units
The Mantoux test is unreliable in renal disease, and appears to have lead to diagnostic nihilism with respect to latent TB infection...
..The IGRA test gives fewer indeterminate and positive results than we expected from overseas reports. Those identified as having LTBI have all been commenced on isoniazid therapy, apart from two patients who are not expected to survive long term. Treatment has been simplified by using directly observed therapy when patients receive dialysis. Those with negative and indeterminate IGRA results will be carefully followed, enabling further clinical validation of the test. Most importantly, the IGRA test has given greater confidence to the renal unit staff and has resulted in active management of LTBI in a high risk group.
