April 18, 2010

These changes in latitudes, changes in attitudes; Nothing remains quite the same*

More info from the Southeastern National Tuberculosis Center Webinar, this time from Dr. Thomas Dobbs and deals with the integration of QuantiFERON TB Gold In Tube (QFT-GIT) into the public health of Mississippi.

Without the explanatory text it is a little difficult to get a handle on what they were doing. At first they appear to be using QFT-GIT for those that have prior BCG, poor rate of return, TB suspects and HIV positive. This is in keeping with provisional CDC guidelines, which is to be expected as the SNTC is funded by the CDC.

However, they then use QFT-GIT to confirm a TST+ which is contrary to the same provisional CDC guidelines;



It's possible that the confirmation of TST+ was limited to 56 individuals




Costs do not seem to be an ongoing issue - the savings from not treating TST false positives appear to balance out the increased cost of QFT-GIT supplies

They seemed to have worked out the logisitics OK, the extended storage time of QFT-GIT allowed them to centralise processing




Confidence in QFT-GIT was worth noting


Confidence is critical - when you face 9 months of medication which has the potential to ruin your liver you want to very sure that you are doing the right thing. This confidence applies to both patients and doctors with health care workers often being both.

* it just seemed appropriate to borrow a few lines from that Mississippian, Jimmy Buffett