"The newer interferon gamma tests for latent TB may offer some advantages over the current internationally recognised standard test - the Mantoux test. However, despite the studies that have been carried out since the original NICE TB guidance was published, important questions remain unanswered about the potential role of these new tests in clinical practice in the UK. The draft guideline therefore adopts a cautious, pragmatic approach by recommending that for many cases the most effective way to diagnose latent TB infection is a Mantoux test followed, depending on the result, by an IGT test."Despite there being no gold test for latent TB the skin test is now an internationally recognised standard test...
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