The performance of QuantiFERON-tuberculosis (TB) Gold-In-Tube assay was compared with the tuberculin skin test for the diagnosis of TB among children. It was shown that among non Bacille Calmette Guerin immunized children, agreement between tests was excellent both in those with TB disease and in TB contacts. Among Bacille Calmette Guerin immunized children, agreement was fair in those with active disease and poor among TB contacts. It is concluded that QuantiFERON-TB Gold-In-Tube compares with the tuberculin skin test in the diagnosis of TB disease and latent tuberculosis infection in TB contacts among children and has enhanced specificity.
November 25, 2010
More of the same.
From the Pediatric Infectious Disease Journal