Hot off the presses, from
Japan;
Our data suggested that QFT-G had high sensitivity and specificity in HIV-infected populations with CD4+ greater than 50/μL. However, QFT-G did not perform well in HIV-positive patients with CD4+ less than 50/μL.
The comparison was made between QFT and TST
QFT-G appeared to have at least as good sensitivity as the TST and significantly better specificity, but the number of subjects was insufficient to make definitive conclusions.
As always, the devil is in the detail
We used the liquid antigen version of the QFT-G test, which has been replaced by the In-Tube version of the test (QFT-GIT) in most countries worldwide. This makes comparisons of our results with those from other studies difficult as most other studies have used QFT-GIT. Since Harada et al. have shown that QFT-GIT has higher sensitivity than QFT-G with the same high specificity [21], it could be expected that the better performance would be obtained than that obtained in this study.
